In toxicology and pharmacology data from chemistry, biology, informatics, and human or ecosystem health science merge and toxicological metadata need to become interoperable and compliant with existing ontology-based data infrastructures of these fields.
A team from three Helmholtz programs ( Earth and Environment , Information , and Health ) will review existing metadata standards and ontologies across fields and generate an integrative, suitable ontology for the annotation of toxicological/pharmacological data and workflows from the experimental design to the data deposit in repositories.
We will establish a metadata framework for the FAIR description of exposure and experimental settings interlinked with chemical IDs and data processing workflows using ‘omics data, which will be implemented into the community-based “Galaxy” project. This will enable interoperability between disciplines to address the grand challenges of chemical pollution and human and ecosystem health.